Best hotels in Clayton
Best hotels in Clayton: the best-rated on Staylist is Clayton Plaza Hotel & Extended Stay (AI score 8.1, typically $155 a night); the best-rated under $250 is AC Hotel St. Louis Clayton (AI score 7.3, typically $227 a night).
More about hotels in Clayton
Staylist lists 8 hotels in Clayton, United States, each with a booking link. Across the 8 with a previously observed price, typical nightly rates run from about $155 to $257, with the middle around $219. Of the 6 with listed amenities, common ones include gym (100%), wi-fi in public areas (100%), restaurant (83%), bar (67%). Guests most often mention great rooms.
- 18.1Clayton Plaza Hotel & Extended Stay3-star · 510 m to Clayton$155 / night
- 28.0The Ritz-Carlton, St. Louis5-star · 960 m to Clayton$629 / night
- 37.6Residence Inn St. Louis Clayton3-star · 820 m to Clayton$322 / night
- 47.3AC Hotel St. Louis Clayton4-star · 170 m to Clayton$227 / night
- 57.6Hampton Inn & Suites Clayton/St. Louis-Galleria Area3-star · 1.0 km to Clayton$219 / night
- 67.4Le Méridien St. Louis Clayton4-star · 460 m to Clayton$257 / night
- 76.5Seven Gables Inn, St. Louis West, a Tribute Portfolio HotelClayton$214 / nightNo photo yet
- 86.2Comfort Suites Clayton - GarnerClayton$147 / nightNo photo yet
Previously observed price; confirm current price and availability. Data updated 2 October 2026. How Staylist ranks hotels.