4-Star Hotels in Louisville

4-star hotels in Louisville, United States: Staylist World lists 11 four-star hotels, ranked by score. Across the 11 with a previously observed price, typical nightly rates run from about $208 to $299 (median $263, versus $134 for the 53 priced Louisville hotels).

The highest-rated is Hotel Distil, Autograph Collection.

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  1. Hotel Distil, Autograph Collection
    18.7Hotel Distil, Autograph Collection4-star$299 / night
  2. Omni Louisville Hotel
    29.0Omni Louisville Hotel4-star$269 / night
  3. 21C Museum Hotel Louisville
    38.921C Museum Hotel Louisville4-star$208 / night
  4. The Brown Hotel
    49.1The Brown Hotel4-star$157 / night
  5. Hotel Genevieve
    58.2Hotel Genevieve4-star$224 / night
  6. Moxy Louisville Downtown
    68.0Moxy Louisville Downtown4-star$263 / night
  7. Hyatt Regency Louisville
    78.8Hyatt Regency Louisville4-star$326 / night
  8. The Seelbach Hilton Louisville
    88.2The Seelbach Hilton Louisville4-star$198 / night
  9. Louisville Marriott Downtown
    97.7Louisville Marriott Downtown4-star$423 / night
  10. Embassy Suites by Hilton Louisville Downtown
    109.1Embassy Suites by Hilton Louisville Downtown4-star$330 / night
  11. Galt House Hotel, Trademark Collection by Wyndham
    117.6Galt House Hotel, Trademark Collection by Wyndham4-star$261 / night

Based on the star rating and prices collected for each hotel. Previously observed price; confirm current price and availability. Data updated 2 October 2026. How Staylist ranks hotels.

4-Star Hotels in Louisville: 11 Top Picks · Staylist World